人们一提到更年期，脑海中就会立刻出现相关词汇，如中老年妇女、衰老、情绪异常等。因为大多数人都认为更年期是女性的专属。其实男人也有更年期，只是常常被大家忽略。有些人甚至在不知情的情况下经历了更年期。
男性更年期是指男性激素分泌在青年时期达到顶峰后逐渐下降而引起的一系列生理变化和临床症状。40岁至70岁的男性中，约有40%会出现一些症状。LOH的症状非常复杂，包括身体和身体症状失眠、多梦、食欲不振、皮肤和肌肉松弛、骨骼和关节疼痛、经常感到腰酸腿软、腹部肥胖等。精神不集中、记忆力减退、健忘、效率低下、急躁、易怒和焦虑。Male menopause refers to a series of physiological changes and clinical symptoms caused by the gradual decline of male hormone secretion after reaching its peak in youth. About 40% of men between the ages of 40 and 70 will experience some symptoms. The symptoms of LOH are very complex, including physical and physical symptoms of insomnia, dreaminess, loss of appetite, skin and muscle relaxation, bone and joint pain, often feel sore waist and soft legs, abdominal obesity, etc. Mental inattention, memory loss, forgetfulness, low efficiency, impatience, irritability and anxiety.
无论男女，更年期是每个人都有的生理过程，是由盛向衰的过渡阶段。但与女性不同的是，男性更年期是一个更长、渐进的过程。它通常从40岁或45岁开始，并在接下来的20年左右波动。
其实很多人对男性更年期还持怀疑态度，认为我没有什么明显的症状啊?这是因为男性更年期有明显的个体差异，相当一部分男性更年期比较轻微，甚至不知道更年期已经不知不觉地进入老年。In fact, many people are still skeptical about male menopause, thinking that I do not have any obvious symptoms ah? This is because there are obvious individual differences in male menopause, a considerable number of men are relatively mild, and even unaware of menopause has entered old age unconsciously.
男性更年期与NMN有何关系?根据日本eunmn营养学家的说法有以下两个方面。
首先，男性的睾酮水平从中年开始以每年0.5到2的速度逐渐下降，睾酮是一种类固醇激素，对男性非常重要。主要用于维持男性身体机能、肌肉力量和质量，维持骨密度。男性更年期与睾酮水平密切相关。睾酮产生实验表明，通过EUNMN介导SIRT1反应来帮助产生睾酮。SIRT1是一种依赖NAD+的去乙酰化酶。NAD+介导SIRT1调节类固醇的环境平衡，NAD+含量降低会导致SIRT1功能减弱，睾酮含量降低。增加NAD+可以促进神经递质多巴胺的合成，增强神经系统的活力，改善情绪和精神状态。
美国内华达大学医学院生理学和细胞生物学学院发表的一篇论文表明，NAD+作为一种神经递质，可以舒缓平滑肌细胞。NAD+受大脑调控和释放，作用于血小板源性生长因子受体A释放钙离子，激活钾离子通道释放钾离子，形成抑制性连接电位。导致平滑肌细胞扩张。NAD+在这个过程中消耗很快，如果不能及时补充，可能会造成平滑肌细胞难以扩张，从而影响夫妻生活。The School of Physiology and Cell Biology at the University of Nevada School of Medicine published a paper showing that NAD+ acts as a neurotransmitter to soothe smooth muscle cells. NAD+ is regulated and released by the brain, acting on platelet-derived growth factor receptor A to release calcium ions, activating potassium ion channels to release potassium ions, and forming inhibitory linking potentials. Which directs smooth muscle cells to dilate. NAD+ is consumed quickly in this process, and if it cannot be supplemented in time, it may cause smooth muscle cells to be difficult to dilate, thus affecting the life of husband and wife.
其次，认知功能是指人体高级中枢神经系统识别物质和获取知识，并将其转化为内在活力和心理活动的能力和过程。它主要是指人脑对环境的认识和对事物的理解所进行的持续不断的思维活动过程，以及执行能力。包括学习、记忆、语言、计算、心理、情感、行为、表达、空间定向、分析判断能力和反应能力，以及自我和环境决定能力。
在日本的临床试验中得到证实。增加EUNMN的摄入量已被证明可以增强健康的大脑功能，并可能预防与年龄相关的认知功能丧失。通过增强大脑线粒体活力，改变供氧能力，减少氧化物积累，保护大脑神经，同时改善脑血流和前额叶皮层氧代谢的影响，提高认知和注意力，以及抗压力、焦虑和疲劳。Confirmed in a clinical trial in Japan. Increasing NMN intake has been shown to enhance healthy brain function and may prevent age-related loss of cognitive function. By enhancing the brain's mitochondrial vitality, changing oxygen supply capacity, reducing oxide accumulation, and protecting the brain's nerves, while improving the impact of cerebral blood flow and oxygen metabolism in the prefrontal cortex, improving cognition and attention, as well as resistance to stress, anxiety and fatigue.
加强身心素质，合理安排生活和工作对男性更年期非常重要。
生活就是运动，这对中老年男性尤其重要!体育锻炼重要在坚持，强调适度切不可三天打鱼，两天晒网，闲做，忙不做。世界卫生组织建议成年人每周锻炼5次，每次30分钟。而且运动强度至少要适中，如果你是运动爱好者，可以继续按照适合自己的运动量进行。
加强自我管理。要控制工作量、控制情绪、控制饮食。
有研究表明经常饮酒、吸烟、大量饮浓茶或浓咖啡不合理的膳食习惯、夜班工作者强脑力劳动者、长期处于紧张状态的人易出现亚健康状态和更年期综合征症状。所以要控制工作量、控制情绪、控制饮食才能更好地度过更年期。
Strengthening physical and psychological quality reasonable arrangement of life and work is very important for male menopause.Life is sport, which is especially important for middle-aged and elderly men! Physical exercise is important in persistence, emphasis on moderation must not be three days fishing, two days drying nets, free to do, busy do not do. The World Health Organization recommends 30 minutes of exercise five times a week for adults. And the exercise should be at least moderate intensity, if you are a sports enthusiast, you can continue to follow the amount of exercise that is suitable for you.
